Volume 1: Section 1: Cardiovascular disease: past, present, and future. A history of the cardiac diseases, and the development of cardiovascular medicine as a specialty -- The global burden of cardiovascular diseases -- Assessing and improving the quality of care in cardiovascular medicine -- Section 2: Foundations of cardiovascular medicine. Functional anatomy of the heart -- Normal physiology of the cardiovascular system -- Molecular and cellular biology of the heart -- Biology of the vessel wall -- Molecular and cellular development of the heart -- Genetic basis of cardiovascular disease -- Stem cells and the cardiovascular system -- Section 3: Evaluation of the patient. The history, physical examination, and cardiac auscultation -- Surface electrocardiography -- Electrocardiographic exercise testing -- Cardiac radiography -- Echocardiography -- Magnetic resonance imaging of the heart -- Computed tomography of the heart -- Nuclear cardiology -- Positron emission tomography in heart disease -- Cardiac catheterization, cardiac angiography, and coronary blood flow and pressure measurements -- Coronary intravascular imaging -- Magnetic resonance imaging and computed tomography of the vascular system -- Section 4: Systemic arterial hypertension. Epidemiology of hypertension -- Pathophysiology of hypertension -- Diagnosis and treatment of hypertension -- Section 5: Metabolic disorders and cardiovascular disease. The metabolic syndrome -- Obesity and cardiovascular disease -- Diabetes and cardiovascular disease -- Hyperlipidemia -- Section 6: Cigarette smoking and cardiovascular diseases. Epidemiology of smoking and pathophysiology of cardiovascular damage -- Preventing and mitigating smoking-related heart disease -- Section 7: Atherosclerosis and coronary heart disease. Atherothrombosis: disease burden, activity, and vulnerability -- Coronary thrombosis: local and systemic factors -- Coronary blood flow and myocardial ischemia -- Nonobstructive atherosclerotic and nonatherosclerotic coronary heart disease -- Definitions of acute coronary syndromes -- Pathology of myocardial infarction and sudden death -- Molecular and cellular mechanisms of myocardial ischemia/reperfusion injury -- Evaluation and management of non -- ST-segment elevation myocardial infarction -- ST-segment elevation myocardial infarction -- Antiplatelet and anticoagulant therapy in acute coronary syndromes -- Percutaneous coronary interventions in acute myocardial infarction and acute coronary syndromes -- The evaluation and management of stable ischemic heart disease -- Coronary artery bypass grafting and percutaneous interventions in stable ischemic heart disease -- Rehabilitation of the patient with coronary heart disease -- Section 8: Valvular heart disease. Acute rheumatic fever -- Aortic valve disease -- Degenerative mitral valve disease -- Ischemic mitral regurgitation -- Mitral stenosis -- Tricuspid and pulmonary valve disease -- Prosthetic heart valves -- Antithrombotic therapy for valvular heart disease -- Management of mixed valvular heart disease -- Index.

Volume 2: Section 9: Congenital heart disease. Mendelian basis of congenital and other cardiovascular diseases -- Congenital heart disease in adolescents and adults -- Section 10: Myocardial, pericardial, and endocardial diseases. Classification of cardiomyopathies -- Dilated cardiomyopathy -- Hypertrophic cardiomyopathies -- Left ventricular noncompaction -- Restrictive heart diseases -- Arrhythmogenic cardiomyopathy -- Myocarditis -- The athlete and the cardiovascular system -- Cardiovascular disease in the elderly: pathophysiology and clinical implications -- Pericardial diseases -- Infective endocarditis -- Section 11: Heart failure. Pathophysiology of heart failure -- The epidemiology of heart failure -- The diagnosis and management of chronic heart failure -- Evaluation and management of acute heart failure -- Cardiac transplantation -- Mechanically assisted circulation -- Section 12: Cardiopulmonary disease. Pulmonary hypertension -- Pulmonary embolism -- Cor pulmonale: the heart in parenchymal lung disease -- Sleep-disordered breathing and cardiac disease -- Section 13: Rhythm and conduction disorders. Electrophysiologic anatomy -- Mechanisms of cardiac arrhythmias and conduction disturbances -- Genetics of channelopathies and clinical implications -- Approach to the patient with cardiac arrhythmias -- Invasive diagnostic electrophysiology -- Atrial fibrillation, atrial flutter, and atrial tachycardia -- Supraventricular tachycardia: atrial tachycardia, atrioventricular nodal reentry, and wolff-parkinson-white syndrome -- Ventricular arrhythmias -- Bradyarrhythmias -- Antiarrhythmic drugs -- Catheter-ablative techniques -- Pacemakers and defibrillators -- Diagnosis and management of syncope -- Sudden cardiac death -- Cardiopulmonary and cardiocerebral resuscitation -- Section 14: Diseases of the great vessels and peripheral vessels. Diseases of the aorta -- Cerebrovascular disease and neurologic manifestations of heart disease -- Carotid artery stenting -- Diagnosis and management of diseases of the peripheral arteries -- Diagnosis and management of diseases of the peripheral venous system -- Section 15: Miscellaneous conditions and cardiovascular disease -- Perioperative evaluation for noncardiac surgery -- Anesthesia and the patient with cardiovascular disease -- Rheumatologic diseases and the cardiovascular system -- The diagnosis and management of cardiovascular disease in patients with cancer -- HIV/AIDS and the cardiovascular system -- Heart disease in pregnancy -- Traumatic heart disease -- The kidney in heart disease -- Exercise in health and cardiovascular disease -- Section 16: Populations and social determinants of cardiovascular disease. Social determinants of cardiovascular disease -- Women and ischemic heart disease: an evolving saga -- Race, ethnicity, and cardiovascular disease -- Environment and heart disease -- Behavioral cardiology: epidemiology, pathophysiology, and clinical management -- Economics and cost-effectiveness in cardiology -- Index.